Plume collimation for laser ablation electrospray ionization mass spectrometry
US8829426B2 · kind B2 · utility
10Cited by
42References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 16, 2012 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Jul 16, 2032 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/165
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
In various embodiments, a device may generally comprise a capillary having a first end and a second end; a laser to emit energy at a sample in the capillary to ablate the sample and generate an ablation plume in the capillary; an electrospray apparatus to generate an electrospray plume to intercept the ablation plume to produce ions; and a mass spectrometer having an ion transfer inlet to capture the ions. The ablation plume may comprise a collimated ablation plume. The device may comprise a flow cytometer. Methods of making and using the same are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.