Methods and systems for Raman and optical cross-interrogation in flow-through silicon membranes
US8830450B2 · kind B2 · utility
5Cited by
20References
25Claims
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Key dates
| Filing date | Dec 1, 2010 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Aug 17, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B2006/12176
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Cross-interrogating photonic detection systems and methods are shown. A flow through photonic crystal membrane with a surface enhanced Raman scattering (SERS) substrate is provided with pores which are distributed along multiple regions. The pores of one region have walls to which a first type of target specific anchor can be attached, while pores of another region have walls to which a second type of target specific anchor can be attached. An optical arrangement out-of-plane to the SERS substrate is also provided for enhanced sensitivity and identification of target organisms.
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