Devices and methods for optoelectronic manipulation of small particles
US8834698B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2010 |
| Grant date | Sep 16, 2014 |
| Priority date | — |
| Expiry date | Apr 16, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/305
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for sorting cells in a biological sample comprising a first type of cells and a second type of cells may comprise introducing the biological sample into a chamber comprising a first surface and a second surface, wherein the first surface is associated with a transparent electrode and the second surface is associated with a photoconductive portion of an electrode. The method may further comprise moving incident light and the photoconductive portion relative to one another so as to illuminate regions of the photoconductive portion and modulate an electric field in the chamber in proximity to the illuminated regions. The method may further comprise separating the first type of cells from the second type of cells in the chamber via dielectrophoretic movement of the first type of cells and the second type of cells caused by the modulated electric field, wherein a dielectrophoretic characteristic of at least one of the first type of cells and the second type of cells has been modified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.