Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for treatment of inflammation, asthma and COPD

US8835440B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Heiner Ebel · Biberach an der Riß, DE
• Sara Frattini · Castelleone, IT
• Riccardo Giovannini · Verona, IT
• Christoph Hoenke · Ingelheim am Rhein, DE
• Thomas Trieselmann · Ochsenhausen, DE
• Patrick Tielmann · Bad Soden am Taunus, DE
• Stefan Scheuerer · Warthausen, DE
• Silke Hobbie · Biberach, DE
• Frank Buettner · Biberach an der Riß, DE

Key dates

• Filing date: Jul 24, 2013
• Grant date: Sep 16, 2014
• Expiry date: Jul 24, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.