Substituted indazole and aza-indazole derivatives as gamma secretase modulators
US8835482B2 · kind B2 · utility
0Cited by
2References
10Claims
0Family size
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Key dates
| Filing date | May 5, 2010 |
| Grant date | Sep 16, 2014 |
| Priority date | — |
| Expiry date | Jan 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is concerned with novel substituted indazole and aza-indazole derivatives of Formula (I)wherein R1, R2, R3, R4, Y, A1, A2, A3, A4, X1, X2, X3 and Het1 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.