Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives

US8835633B2 · kind B2 · utility

Assignee

• Janssen Pharmaceuticals, Inc. · BE

Inventors

• Sergio Cesco-Cancian · Bethlehem, US
• Jeffrey S. Grimm · Somerville, US
• Neelakandha S. Mani · San Diego, US
• Christopher M. Mapes · Village of La Jolla, US
• David C. Palmer · Doylestown, US
• Daniel J. Pippel · Del Mar, US
• Tong Xiao · Edison, US
• Diego Broggini · Schaffhausen, CH
• Susanne Lochner · Singen, DE

Key dates

• Filing date: Mar 22, 2012
• Grant date: Sep 16, 2014
• Expiry date: Jan 19, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H4 receptor modulators and processes for the preparation of such compounds.