Substituted 4-aminocyclohexane derivatives

US8835689B2 · kind B2 · utility

Assignee

• GRÜNENTHAL GMBH · DE

Inventors

• Bert Nolte · Aachen, DE
• Wolfgang Schröder · Aachen, DE
• Klaus Linz · Rheinbach, DE
• Werner Englberger · Stolberg, DE
• Hans Schick · Berlin, DE
• Heinz Graubaum · Berlin, DE
• Birgit ROLOFF · Berlin, DE
• Sigrid Ozegowski · Berlin, DE
• József Bálint · Budapest, HU
• Helmut Sonnenschein · Berlin, DE

Key dates

• Filing date: Apr 24, 2012
• Grant date: Sep 16, 2014
• Expiry date: Apr 24, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.