Tamper-resistant pharmaceutical compositions of opioids and other drugs

US8840928B2 · kind B2 · utility

Assignee

• Collegium Pharmaceutical, Inc. · US

Inventors

• Roman V. Rariy · Brookline, US
• Alison Fleming · Mansfield, US
• Jane Hirsh · Wellesley, US
• Said Saim · Lawrence, US
• Ravi K. Varanasi · North Providence, US

Key dates

• Filing date: Dec 10, 2010
• Grant date: Sep 23, 2014
• Expiry date: Dec 10, 2030

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B29C70/60
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.