Methods for the detection and monitoring of acute myocardial infarction

US8841084B2 · kind B2 · utility

Assignees

• UNIVERSITY OF CONNECTICUT · US
• Mayo Foundation for Medical Education and Research · US

Inventors

• Bruce Liang · Avon, US
• Heiko Schmitt · Eppelheim, DE
• Michael Azrin · Southington, US
• Christopher C. Pickett · Farmington, US
• Allan S. Jaffe · Rochester, US

Key dates

• Filing date: May 12, 2011
• Grant date: Sep 23, 2014
• Expiry date: May 12, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed herein are methods of detecting and/or prognosing myocardial infarction by detecting a proteolytic fragment of caspase-3 such as the p17 fragment or the p12 fragment. The myocardial infarction can be STEMI or NSTEMI.