Patent · US Active

Method for mRNA stabilization

US8841088B2 · kind B2 · utility

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9Claims

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Assignee

DSM IP ASSETS B.V. · NL

Inventors

Abel Ferrandez · Kaiseraugst, CH
John B. Perkins · Reading, US
Michèle Schaber · Basel, CH

Key dates

Filing date	Dec 1, 2006
Grant date	Sep 23, 2014
Priority date	—
Expiry date	Oct 26, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/67
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method to increase the production of a desired chemical compound in a microorganism by introduction of a DNA sequence at the 5′ end of the encoding DNA gene sequence capable of forming a stem loop and capable of increasing the stability of mRNA transcripts from one or more genes, thus stabilized mRNAs, corresponding DNA sequences and microorganisms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.