Combined detection instrument for culture specimen containers and instrument for identification and/or characterization of a microbial agent in a sample
US8841118B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 14, 2010 |
| Grant date | Sep 23, 2014 |
| Priority date | — |
| Expiry date | Jul 6, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/0465
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A detection instrument determines whether a specimen container (e.g., blood culture bottle) is positive for presence of microbial agent growth therein. When the container is deemed positive it is made available (e.g, transferred or exposed to) to an automated instrument performing identification and/or characterization of the microbial agent. The identification and/or characterization instrument removes a portion of the sample from the specimen container and places it into a disposable separation and concentration device. The microbial agent is concentrated via optional selective lysis of non-microbial agent cellular material which may be present and centrifugation. A reading module reads the concentrated microbial agent using spectroscopic methods, e.g., measurements of intrinsic fluorescence. Such interrogation may occur while the microbial agent remains concentrated in the disposable device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.