Methods for producing hair microfollicles and de novo papillae and their use for in vitro tests and in vivo implantations

US8841124B2 · kind B2 · utility

Assignee

• TECHNISCHE UNIVERSITÄT BERLIN · DE

Inventors

• Gerd Lindner · Berlin, DE
• Roland Lauster · Berlin, DE

Key dates

• Filing date: Mar 23, 2009
• Grant date: Sep 23, 2014
• Expiry date: Oct 28, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/54
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a method for producing hair microfollicles comprising the steps of: a) providing de novopapillae, b) providing other cell populations selected from the group of fibroblasts, keratinocytes and melanocytes, and co-culturing the de novopapillae with at least one other cell population in non-adherent culture vessels. The present invention relates also to methods of producing de novo papillae usable in said method for producing hair microfollicles.