Heterocyclic compounds as autotaxin inhibitors

US8841324B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Wolfgang Staehle · Ingelheim am Rhein, DE
• Kai Schiemann · Darmstadt, DE
• Melanie Schultz · Darmstadt, DE

Key dates

• Filing date: Mar 3, 2010
• Grant date: Sep 23, 2014
• Expiry date: Dec 28, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I), in which Het, R, X, Y, R1 and p have the meanings indicated in claim 1, are autotaxin inhibitors and can be employed for the treatment of tumors.