Antidiabetic compounds

US8841413B2 · kind B2 · utility

Assignee

• Cadila Healthcare Ltd. · IN

Inventors

• Rajesh Bahekar · Ahmedabad, IN
• Braj Bhushan Lohray · Hyderabad, IN
• Vidya Bhushan Lohray · Hyderabad, IN
• Mukul Jain · Sayla, IN
• Kaushik Banerjee · Sayla, IN
• Pankaj Ramanbhai Patel · Sayla, IN

Key dates

• Filing date: Sep 28, 2007
• Grant date: Sep 23, 2014
• Expiry date: Jan 18, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/605
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides novel peptidomimetics, of formula (I), which primarily act as glucose dependent insulin secretagogues. Furthermore, it was found that these peptidomimetics showed glucagon receptor antagonistic activity, along with the GLP-1 receptor agonistic activity.A-Z1—Z2—Z3—Z4—Z5—Z6—Z7—Z8—Z9—Z10—Z11—B  (I)