S100A9 interaction screening method
US8841421B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 24, 2008 |
| Grant date | Sep 23, 2014 |
| Priority date | — |
| Expiry date | Oct 18, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of identifying a compound for use in therapy which modulates the interaction of S1OO A9 with a ligand comprising:—determining whether a candidate compound is capable of modulating the interaction of S1OO A9 with RAGE or the interaction of S1OO A9 with a TLR (Toll like receptor), or—determining whether a candidate compound is capable of binding to S100A9 in a manner which disrupts binding of S1OO A9 with RAGE or the binding of S100A9 with a TLR, to thereby identify whether the compound may be used in therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.