Patent · US Active

S100A9 interaction screening method

US8841421B2 · kind B2 · utility

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10Claims
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Assignee

Inventors

Key dates

Filing dateApr 24, 2008
Grant dateSep 23, 2014
Priority date
Expiry dateOct 18, 2030

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2500/00
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of identifying a compound for use in therapy which modulates the interaction of S1OO A9 with a ligand comprising:—determining whether a candidate compound is capable of modulating the interaction of S1OO A9 with RAGE or the interaction of S1OO A9 with a TLR (Toll like receptor), or—determining whether a candidate compound is capable of binding to S100A9 in a manner which disrupts binding of S1OO A9 with RAGE or the binding of S100A9 with a TLR, to thereby identify whether the compound may be used in therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.