MDCK cell lines supporting viral growth to high titers and bioreactor process using the same
US8846032B2 · kind B2 · utility
0Cited by
14References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 27, 2012 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Aug 27, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16252
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel MDCK cells which can be to grow viruses, e.g., influenza viruses, in cell culture to higher titer than previously possible. The MDCK cells can be adapted to serum-free culture medium. The present invention further relates to cell culture compositions comprising the MDCK cells and cultivation methods for growing the MDCK cells. The present invention further relates to methods for producing influenza viruses in cell culture using the MDCK cells of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.