Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
US8846034B2 · kind B2 · utility
11Cited by
71References
58Claims
0Family size
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Key dates
| Filing date | Oct 24, 2012 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Oct 28, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and diagnostic agents for identification of subjects for cancer treatment with an anti-hyaluronan agent, such as a hyaluronan-degrading enzyme, are provided. Diagnostic agents for the detection and quantification of hyaluronan in a biological sample and monitoring cancer treatment with an anti-hyaluronan agent, for example a hyaluronan-degrading enzyme, are provided. Combinations and kits for use in practicing the methods also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.