Monoclonal antibodies against HMGB1
US8846047B2 · kind B2 · utility
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49References
16Claims
0Family size
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Inventors
Key dates
| Filing date | Oct 4, 2010 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Oct 4, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.