Matrix for sustained, invariant and independent release of active compounds

US8846090B2 · kind B2 · utility

Assignee

• Euro-Celtique S.A. · LU

Inventors

• Bianca BRÖGMANN · Ulm, DE
• Silke Mühlau · Hamburg, DE
• Christof Spitzley · Hadamar, DE

Key dates

• Filing date: Jan 11, 2012
• Grant date: Sep 30, 2014
• Expiry date: Jan 11, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.