Asynchronous magnetic bead rotation sensing systems and methods

US8846331B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• Brandon H. McNaughton · Ann Arbor, US
• Paivo Kinnunen · Ann Arbor, US
• Raoul Kopelman · Ann Arbor, US
• Alan Hunt · Plymouth, US
• Roy Clarke · Ann Arbor, US
• Irene Sinn · Ann Arbor, US
• Remy Elbez · Ann Arbor, US
• Theodore Albertson · Bloomfield, US

Key dates

• Filing date: Aug 29, 2011
• Grant date: Sep 30, 2014
• Expiry date: Aug 29, 2031

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/569
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Described herein are various methods, devices and systems for performing asynchronous magnetic bead rotation (AMBR) to detect and monitor cellular growth and/or behavior. Cluster rotation of magnetic particles for AMBR is descried. In particular, described herein are systems for the parallel analysis of multiple wells of a sample plate. Also described herein are methods for controlling the illumination and imaging of rotating magnetic particles.