Method and means for producing high titer, safe recombinant lentivirus vectors
US8846385B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Jul 26, 2006 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Mar 3, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.