Patent · US Active

Promoters exhibiting endothelial cell specificity and methods of using same

US8846401B2 · kind B2 · utility

5Cited by

47References

34Claims

0Family size

Assignee

VASCULAR BIOGENICS LTD. · IL

Inventors

Dror Harats · Ramat Gan, IL
Eyal Breitbart · Pardes Hana-Karkur, IL
Nira Bloom · Hod HaSharon, IL

Key dates

Filing date	Apr 24, 2012
Grant date	Sep 30, 2014
Priority date	—
Expiry date	Apr 24, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2840/445
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An isolated polynucleotide functional as a promoter in eukaryotic cells is disclosed. The isolated polynucleotide includes an endothelial specific enhancer element as detailed herein. Further disclosed is a method of expressing a nucleic acid sequence of interest in endothelial cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.