Derivatives, reagents, and immunoassay for detecting levetiracetam
US8846411B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 2010 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Jun 9, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/9473
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Levetiracetam (LEV) derivatives, methods for synthesizing LEV derivatives, and immunodiagnostic assays for LEV. The synthesis methods described herein include chirally-selective, liquid-phase synthesis steps to produce selected LEV derivatives in high-yield. LEV derivatives can include operative groups, such as: immunogenic moieties that can be used to prepare anti-LEV antibodies; antigenic moieties that can be used in immunodiagnostic assays for LEV; or tracer moieties that can be used in immunodiagnostic assays. Additionally, the LEV derivatives can be used in immunodiagnostic assays to compete with LEV for anti-LEV antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.