Patent · US Active

Pyrrolidone derivatives for use as MetAP-2 inhibitors

US8846694B2 · kind B2 · utility

31Cited by

1References

2Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Timo Heinrich · Groß-Umstadt, DE
Mireille Krier · Mühltal, DE
Thorsten Knoechel · Darmstadt, DE
Alfred Jonczyk · Darmstadt, DE
Frank Zenke · Darmstadt, DE
Holger Enderle · Windesheim, DE

Key dates

Filing date	May 13, 2009
Grant date	Sep 30, 2014
Priority date	—
Expiry date	May 31, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of the formula (I), in which R, X, Y, Z, R3 and R4 have the meanings indicated in claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumours.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.