Crystal of a free tricyclic pyrazolopyrimidine derivative
US8846703B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Feb 21, 2013 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Feb 21, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
To provide a crystal of a tricyclic pyrazolopyrimidine compound inhibiting the effect of HSP90. The present invention provides a crystal of 2-{4-amino-2-[(3-chloro-4-methoxy-5-methylpyridin-2-yl)methyl]-2,7-dihydro-6-thia-1,2,3,5-tetraazabenzo[cd]azulen-8-yl}-N-methylacetamide which inhibits the ATPase activity of HSP90 and which has antitumor activity, a medicament comprising the same, an anticancer agent comprising the same, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.