Patent · US Active

N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy

US8846741B2 · kind B2 · utility

1Cited by

21References

19Claims

0Family size

Assignees

Abb Vie Inc. · US
Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

Wilhelm Amberg · Ludwigshafen, DE
Udo Lange · Ludwigshafen, DE
Frauke Pohlki · Wiesbaden, DE
Ernesto Santandrea · Zürich, CH
Charles W. Hutchins · Libertyville, US

Key dates

Filing date	Nov 19, 2012
Grant date	Sep 30, 2014
Priority date	—
Expiry date	Nov 19, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D305/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives of the formula (I), (II), (III) or (IV)or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such N-substituted amino-benzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, and the use of such N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives for therapeutic purposes. The N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives are GlyT1 inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.