Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy

US8846743B2 · kind B2 · utility

Assignees

• Abbott Laboratories · US
• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Frauke Pohlki · Wiesbaden, DE
• Udo Lange · Ludwigshafen, DE
• Wilhelm Amberg · Ludwigshafen, DE
• Michael Ochse · Wiesbaden, DE
• Berthold Behl · Ludwigshafen, DE
• Charles W. Hutchins · Libertyville, US

Key dates

• Filing date: Aug 10, 2011
• Grant date: Sep 30, 2014
• Expiry date: Nov 2, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to aminoindane derivatives of the formula (I)or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such aminoindane derivatives, and the use of such aminoindane derivatives for therapeutic purposes. The aminoindane derivatives are GlyT1 inhibitors.