Tissue sealants from plasma derived proteins
US8846849B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 13, 2011 |
| Grant date | Sep 30, 2014 |
| Priority date | — |
| Expiry date | Jan 13, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/14
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention is directed in one embodiment to a tissue adhesive or sealant composition comprising an electrophilic group containing cross-linking compound having a linker moiety of a diglycolic acid, a water soluble core moiety and an electrophilic group that is covalently bonded to the diglycolic acid linker moiety and a nucleophilic group containing protein. In other embodiments, the present invention is directed to a delivery device or a medical device on which the composition has been applied or incorporated therein. The present invention is also directed to a method for sealing tissue using the tissue adhesive or sealant composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.