Method and apparatus for real-time 3D target position estimation by combining single x-ray imaging and external respiratory signals

US8849373B2 · kind B2 · utility

Assignee

• Stanford University · US

Inventors

• Paul J. Keall · Stanford, US
• Amit Sawant · Columbia, US
• Peter G. Maxim · Palo Alto, US
• Yelin Suh · Palo Alto, US
• Lei Xing · Palo Alto, US
• Billy Wiseman Loo · Oakland, US
• Byung Chul Cho · Anyang-si, KR

Key dates

• Filing date: May 12, 2008
• Grant date: Sep 30, 2014
• Expiry date: Aug 17, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B6/541
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method and system are disclosed for estimating internal position information of a target in real-time based on a single gantry-mounted x-ray imager and a respiratory signal. The x-ray imaging is done periodically to limit radiation dosage. Initial parameters for the estimation model are determined in a pre-treatment session using four dimensional computed tomography (4D CT) in combination with a respiratory signal acquired from the patient. The model parameters are updated during treatment based on the periodic x-ray image data and the respiratory signal.