Controlled-release CNS modulating compositions and methods for the treatment of otic disorders

US8852626B2 · kind B2 · utility

Assignees

• OTONOMY, INC. · US
• The Regents of the University of California · US

Inventors

• Jay Lichter · Rancho Santa Fe, US
• Carl Lebel · Malibu, US
• Fabrice Piu · San Diego, US
• Qiang Ye · San Diego, US
• Luis A. Dellamary · San Marcos, US
• Andrew M. Trammel · Olathe, US
• Jeffrey P. Harris · Village of La Jolla, US

Key dates

• Filing date: Mar 20, 2012
• Grant date: Oct 7, 2014
• Expiry date: Mar 20, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).