Patent · US Active

Integrin interaction inhibitors for the treatment of cancer

US8853149B2 · kind B2 · utility

6Cited by
13References
102Claims
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Key dates

Filing dateMar 21, 2011
Grant dateOct 7, 2014
Priority date
Expiry dateMar 21, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective amount of the integrin interaction inhibitor. Data show that integrin interaction inhibitors act synergistically or additively interact with anti-proliferative agents such as doxorubicin, SAHA, arsenic trioxide, and etoposide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.