Patent · US Active

Oligopeptide improving differentiation of osteoblasts

US8853164B2 · kind B2 · utility

1Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 26, 2010
Grant dateOct 7, 2014
Priority date
Expiry dateFeb 26, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L2430/12
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

The present disclosure relates to oligopeptides applicable to a dental implant, which are selected from the group consisting of PEP7 (SEQ ID NO:1), PEP71 (SEQ ID NO:2), EP72 (SEQ ID NO:3), PEP73 (SEQ ID NO:4), PEP74 (SEQ ID NO:5), PEP75 (SEQ ID NO:6) and PEP76 (SEQ ID NO:7). The oligopeptides have very high reactivity for a BMP-specific receptor to increase osteoblastic differentiation and calcification, thereby showing improved osteointegration and osteogenesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.