Oligopeptide improving differentiation of osteoblasts
US8853164B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2010 |
| Grant date | Oct 7, 2014 |
| Priority date | — |
| Expiry date | Feb 26, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/12
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present disclosure relates to oligopeptides applicable to a dental implant, which are selected from the group consisting of PEP7 (SEQ ID NO:1), PEP71 (SEQ ID NO:2), EP72 (SEQ ID NO:3), PEP73 (SEQ ID NO:4), PEP74 (SEQ ID NO:5), PEP75 (SEQ ID NO:6) and PEP76 (SEQ ID NO:7). The oligopeptides have very high reactivity for a BMP-specific receptor to increase osteoblastic differentiation and calcification, thereby showing improved osteointegration and osteogenesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.