Coferons and methods of making and using them
US8853185B2 · kind B2 · utility
2Cited by
2References
5Claims
0Family size
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Key dates
| Filing date | Apr 9, 2009 |
| Grant date | Oct 7, 2014 |
| Priority date | — |
| Expiry date | Jul 21, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/69
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A monomer useful in prepaπng therapeutic compounds includes a diversity element which potentially binds to a target molecule with a dissociation constant of less than 300 11 M and a linker element connected to the diversity element The linker element has a molecular weight less than 500 daltons, is connected, directly or indirectly through a connector, to said diversity element, and is capable of forming a reversible covalent bond or noncovalent interaction with a binding partner of the linker element The monomers can be covalently or non-covalently linked together to form a therapeutic multimer or a precursor thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.