Agents for treating disorders involving modulation of ryanodine receptors
US8853198B2 · kind B2 · utility
4Cited by
4References
29Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 11, 2013 |
| Grant date | Oct 7, 2014 |
| Priority date | — |
| Expiry date | Nov 11, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D285/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.