Patent · US Active

9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazoline-6-yloxy]-1,4-diaza-spiro[5.5] undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof

US8853225B2 · kind B2 · utility

1Cited by

1References

4Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Waldermar Pfrengle · Biberach an der Riß, DE
Guenther Huchler · Biberach an der Riß, DE
Markus Ostermeier · Biberach an der Riß, DE
Peter Sieger · Mittelbiberach, DE

Key dates

Filing date	Jan 27, 2012
Grant date	Oct 7, 2014
Priority date	—
Expiry date	Jun 17, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a compound of formula (I),which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing these compounds, particularly pharmaceutical formulations suitable for inhalation and their use for the treatment of diseases, particularly tumoral diseases, benign prostatic hyperplasia and diseases of the lungs and airways.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.