Patent · US Active

Method for producing intermediates for the production of macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof

US8853249B2 · kind B2 · utility

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8Claims

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Assignees

Helmholtz-Zentrum Für Infektionsforschung GmbH · DE
MEDIZINISCHE HOCHSCHULE HANNOVER · DE
Gottfried Wilhelm Leibniz Universität · DE

Inventors

Markus Kalesse · Burgdorf, DE
Ulrike Eggert · Hannover, DE

Key dates

Filing date	Dec 14, 2010
Grant date	Oct 7, 2014
Priority date	—
Expiry date	May 24, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to an improved method for the synthesis of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.