Patent · US Active

Thalidomide analogs

US8853253B2 · kind B2 · utility

0Cited by

33References

15Claims

0Family size

Assignee

P2D, Inc. · US

Inventors

Nigel H. Greig · Phoenix, US
Harold W. Holloway · Middle River, US
Arnold Brossi · Bethesda, US
Xiaoxiang Zhu · New Brunswick, US
Tony Giordano · Shreveport, US
Qian-Sheng Yu · Timonium, US
William D. Figg · Fairfax, US

Key dates

Filing date	Oct 10, 2012
Grant date	Oct 7, 2014
Priority date	—
Expiry date	Oct 10, 2032

Classification

Technology area (CPC H)Electricity
CPC primaryH04M2250/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.