Substance binding human IgG Fc receptor IIb (FcγRIIb)

US8853363B2 · kind B2 · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Robert Huber · Midland, US
• Peter Sondermann · Stockdorf, DE
• Uwe Jacob · Birkenfeld, DE
• Kerstin Wendt · Brand-Erbisdorf, DE
• Chiara Cabrele · Regensburg, DE
• Luis Moroder · Martinsried, DE

Key dates

• Filing date: Nov 26, 2004
• Grant date: Oct 7, 2014
• Expiry date: Sep 4, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel immunogens carrying conformationally discriminating epitopes (CDEs) and to immunization methods for producing antibodies that specifically recognize proteins with very closely related homologues. In particular, the invention relates to antibodies which are specific for either FcγRIIb or FcγRIIa.