Intermediate for preparing tapentadol or analogues thereof
US8853393B2 · kind B2 · utility
1Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 29, 2011 |
| Grant date | Oct 7, 2014 |
| Priority date | — |
| Expiry date | Jul 29, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/185
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention discloses a novel intermediate for preparing tapentadol and analogues thereof, wherein the structural formula is shown as formula I or II, and the groups are defined as the specification. The invention further discloses a method for preparing the novel intermediate and use of the intermediate for preparing tapentadol and analogues thereof. The invention can remarkably improve the product yield and quality of tapentadol, reduce the production cost, and simplify the production procedure. The preparation process is environment friendly, thus more suitable for the requirements of industrial production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.