Methods for the preparation of lapatinib and the salts thereof
US8853396B2 · kind B2 · utility
2Cited by
1References
14Claims
0Family size
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Inventor
Key dates
| Filing date | Mar 8, 2012 |
| Grant date | Oct 7, 2014 |
| Priority date | — |
| Expiry date | Mar 16, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods for the synthesis of the pharmaceutically active ingredient Lapatinib and the salts thereof are provided. In particular, such methods utilize intermediates in which the hydroxyl function is protected by a tetrahydropyranyl group providing greater solubility of the intermediates in common organic solvents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.