Method and system for capture and use of intact vesicles on electrodeposited hydrophobically modified biopolymer films

US8858883B2 · kind B2 · utility

Assignees

• UNIVERSITY OF MARYLAND, COLLEGE PARK · US
• Wichita State University · US

Inventors

• Matthew Dowling · Washington, US
• Srinivasa R. Raghavan · Silver Spring, US
• Neeraja Dashaputre · College Park, US
• Douglas S. English · Derby, US
• Vishal Javvaji · Chantilly, US
• Gregory F. Payne · Cockeysville, US
• Philip R. DeShong · Silver Spring, US

Key dates

• Filing date: Dec 2, 2011
• Grant date: Oct 14, 2014
• Expiry date: Dec 2, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/11
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A biosensor comprising an electrically conductive substrate coated with a modified chitosan biopolymer that has been electrodeposited on the substrate, wherein said modified chitosan biopolymer comprises at least one vesicle binding molecule. The biosensor is manufactured by a method where a modified chitosan biopolymer is electrodeposited on a substrate. The method is also used to manufacture a modified chitosan biopolymer film by electrodeposition of the chitosan on the substrate and later removing the film from the substrate after electrodeposition. The resulting film can be used in bandages to treat various types of wounds. The biosensor can also be used to detect various analytes in samples.