Methods and compositions for improving efficiency of nucleic acids amplification reactions
US8859205B2 · kind B2 · utility
7Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 7, 2010 |
| Grant date | Oct 14, 2014 |
| Priority date | — |
| Expiry date | Jul 31, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonuclease activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.