Method for detecting replication or colonization of a biological therapeutic
US8859256B2 · kind B2 · utility
35Cited by
60References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 5, 2012 |
| Grant date | Oct 14, 2014 |
| Priority date | — |
| Expiry date | Nov 4, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for detecting replication in or colonization of a host by a biological therapeutic, such as an oncolytic virus, cells administered for cell therapy and gene therapy vectors, are provided. In the methods, a product produced by the biological therapeutic is detected in a sample of tissue or body fluid distinct from the administered therapy or locus thereof, thereby permitting assessment of the therapy and/or monitoring its progress.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.