Patent · US Active

Method for detecting replication or colonization of a biological therapeutic

US8859256B2 · kind B2 · utility

35Cited by
60References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 5, 2012
Grant dateOct 14, 2014
Priority date
Expiry dateNov 4, 2032

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/52
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods for detecting replication in or colonization of a host by a biological therapeutic, such as an oncolytic virus, cells administered for cell therapy and gene therapy vectors, are provided. In the methods, a product produced by the biological therapeutic is detected in a sample of tissue or body fluid distinct from the administered therapy or locus thereof, thereby permitting assessment of the therapy and/or monitoring its progress.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.