Targeted therapeutic proteins
US8859498B2 · kind B2 · utility
2Cited by
69References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 2013 |
| Grant date | Oct 14, 2014 |
| Priority date | — |
| Expiry date | Jun 18, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.