Cytotoxic immunoglobulin

US8859738B2 · kind B2 · utility

Assignee

• F-star Biotechnologische Forschungs- und Entwicklungsges M.B.H. · AT

Inventors

• Gottfried Himmler · Groß-Enzersdorf, AT
• Geert Mudde · Purkersdorf, AT
• Anton Bauer
• Gerda Redl · Groß-Enzersdorf, AT
• Maximillian Woisetschlager · Oberwil, CH

Key dates

• Filing date: Mar 3, 2009
• Grant date: Oct 14, 2014
• Expiry date: Jul 15, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a cytotoxic modular antibody with a molecular weight of up to 6 OkD, specifically binding to a cell surface target with a binding affinity of Kd<10−8 M, a method of producing such antibody and its use as a therapeutic.