Method for preparing ribonucleoside phosphorothioate
US8859755B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Mar 4, 2011 |
| Grant date | Oct 14, 2014 |
| Priority date | — |
| Expiry date | Nov 17, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for preparing a phosphorothioate RNA based on the oxazaphospholidine method, wherein cyanoethoxymethyl group is used instead of tert-butyldimethylsilyl group as a protective group of 2′-hydroxyl group of RNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.