Methods and devices of separating molecular analytes
US8864970B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 2010 |
| Grant date | Oct 21, 2014 |
| Priority date | — |
| Expiry date | Dec 11, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/28
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.