Patent · US Active

High-throughput platform for in-vivo sub-cellular screens on vertebrate larvae

US8865630B2 · kind B2 · utility

2Cited by

1References

23Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Mehmet Fatih Yanik · Watertown, US
Steven Wasserman · Concord, US
Carlos Pardo · Cambridge, US
Cody L. Gilleland · Cambridge, US
Tsung-Yao Chang · Cambridge, US

Key dates

Filing date	Feb 26, 2010
Grant date	Oct 21, 2014
Priority date	—
Expiry date	Dec 10, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG01N1/28
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

High throughput system for in vivo screens on vertebrate larvae. The system includes a source of vertebrate larvae in a liquid medium and loading tube means for aspirating a larva. A detector assembly is provided to differentiate passage of a larva from bubbles and/or debris. An imaging means is provided for both confocal imaging and wide-field fluorescence imaging of the larva. A laser is provided for optical manipulation of the larva.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.