Patent · US Active

Substituted pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors

US8865726B2 · kind B2 · utility

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Key dates

Filing dateSep 3, 2010
Grant dateOct 21, 2014
Priority date
Expiry dateMay 4, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.