Antibacterial agents

US8865736B2 · kind B2 · utility

Assignee

• Biota Scientific Pty Ltd · AU

Inventors

• David Ryall Brown · Yarnton, GB
• Ian Collins · Ware, GB
• Lloyd George Czaplewski · Yarnton, GB
• David John Haydon · Yarnton, GB

Key dates

• Filing date: Nov 28, 2011
• Grant date: Oct 21, 2014
• Expiry date: Dec 12, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I) have antibacterial activity:wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is ═C(R1)—; R1 is hydrogen and R2 is hydrogen, methyl, or fluorine; or R1 and R2 taken together are —CH2—, —CH2CH2, —O—, or, in either orientation, —O—CH2— or —OCH2CH2—; and R3 is a radical of formula -(Alk1)m-(Z)p-(Alk2)n-Q.